Clinical and epidemiological characterization of dengue hemorrhagic fever cases in northeastern, Brazil

Revista da Sociedade Brasileira de Medicina Tropical

Luciano Pamplona De Góes Cavalcanti²  Ivo Castelo Branco Coelho¹  Dina Cortez Lima Feitosa Vilar¹  Susana Glória Silveira Holanda¹  Kiliana Nogueira Farias Da Escóssia¹  Reinaldo Souza-santos¹ 

[1],Federal University of Ceará Graduate Program in Medical Sciences Fortaleza CE ,Brazil

关键词: Dengue hemorrhagic fever;    Epidemiology;    Risk factors;    Dengue hemorrágico;    Epidemiologia;    Fatores de risco;   

DOI  :  10.1590/S0037-86822010000400003

来源: SciELO

【 摘 要 】

INTRODUCTION: The dengue hemorrhagic dengue (DHF) remains an important public health problem in Brazil. The objective of this study was to analyze the epidemiological characteristics of DHF cases during the 2003 epidemic in Ceará. METHODS: Suspected DHF cases with onset of symptoms between January and December 2003 were investigated. RESULTS: 37,964 classic dengue cases and 291 DHF cases were reported. Among the cases discarded, 75.5% were serologically positive but did not meet the criteria recommended by the World Health Organization (WHO). The DHF patients' median age was 30 years (2 - 88). Among the hemorrhagic manifestations, petechiae were the most (32.6%) frequent. Cases of gastrointestinal bleeding, ascites, pericardial pleural effusion, hepatomegaly, hypotension and shock showed higher risk of progression to death (p <0.05). CONCLUSIONS: The introduction of a new serotype (DENV-3) in Ceará, which encountered a susceptible population and high vector density, may have been the primary agent responsible for the magnitude of the epidemic. Timely and appropriate medical care, along with an organized care structure are essential for reducing its lethality.

【 授权许可】

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