Epidemiological and molecular characteristics of HIV-1 infection among female commercial sex workers, men who have sex with men and people living with AIDS in Paraguay

Revista da Sociedade Brasileira de Medicina Tropical

Nicolas Aguayo²  Victor Alberto Laguna-torres¹  Margarita Villafane²  Alma Barboza²  Liliana Sosa²  Gloria Chauca¹  Gladys Carrion¹  Beatriz Coenca²  Juan Perez²  Adolfo Galeano¹  Christian T. Bautista¹  Jose L. Sanchez¹  Jean K. Carr¹  Tadeusz Kochel¹ 

[1] ,Ministry of Health ParaguayAsunción,Paraguay

关键词: HIV/AIDS;    Paraguay;    Epidemiology;    HIV genotypes;    Developing countries;    HIV/AIDS;    Paraguai;    Epidemiologia;    Genótipos HIV;    Países em desenvolvimento;   

DOI  :  10.1590/S0037-86822008000300001

来源: SciELO

【 摘 要 】

An HIV seroprevalence and molecular study was conducted among 935 subjects: 723 female commercial sex workers, 92 men who have sex with men and 120 HIV-positive volunteers. The reported injection drug use rates were 0.7% in female commercial sex workers and 3% in men who have sex with men. Sexually transmitted infections were reported in 265 (37%) of the female commercial sex workers and 38 (41%) of the men who have sex with men. A total of 20 (2.8%) female commercial sex workers and 12 (13%) men who have sex with men became HIV infected during the study period. A history of sexually transmitted infection increased the risk of subsequent HIV infection twofold (adjusted odds ratio of 2.5) among the female commercial sex workers, while cocaine use had an adjusted odds ratios of 6.61 among men who have sex with men. From 130 samples, and based on heteroduplex mobility assaying for the env gene, with sequencing of part of pol and/or full genomes, subtype B was the predominant subtype identified (66%); followed by subtype F (22%) and subtype C (4%). Recombinant CRF12-BF strains were identified in 6% and CRF17_BF was identified in 2%.

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