New evidence of spontaneous cure in human Chagas' disease

Revista da Sociedade Brasileira de Medicina Tropical

Sonia S. Francolino¹  Antonio Fernandez Antunes¹  Rodolfo Talice²  Rachel Rosa¹  Joel Selanikio¹  Joffre Marcondes De Rezende¹  Álvaro J. Romanha¹  João Carlos Pinto Dias¹ 

[1] ,National UniversityMontevideo,Uruguay

关键词: Trypanosoma cruzi;    Chagas' disease;    Spontaneous cure;    Trypanosoma cruzi;    Doença de Chagas;    Cura espontânea;   

DOI  :  10.1590/S0037-86822003000100014

来源: SciELO

【 摘 要 】

A new case of spontaneous cure of human Chagas' disease is described in Uruguay. An 87-year-old man who had a typical acute phase of Trypanosoma cruzi infection in 1947 and never received specific treatment against the disease, when examined in 1998 revealed several completely negative parasitological and serological tests, including traditional serology, PCR and flow cytometry. As a whole, such findings fulfill the current criteria to define the cure of Chagas' disease. Clinical data suggest the possibility of a benign evolution of Chagas' disease in this case, but the basic findings (slight cardiac and esophageal impairment) could also be due to the advanced age of the patient.

【 授权许可】

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