Prospective study of strongyloidosis in patients with hematologic malignancies

Revista da Sociedade Brasileira de Medicina Tropical

Carlos Graeff-teixeira¹  Cristina S.m. Leite¹  Cristina L. Sperhacke¹  Katia Fassina¹  Simone M.g. Petry¹  Tamara Mucenic¹  Cláudio Pandolfi¹  Susana Barcellos¹  Fani Job¹ 

关键词: Strongyloides stercoralis;    Strongyloidosis;    Leukemia;    Lymphoma;    Hematologic malignancies;    Strongyloides stercoralis;    Estrongiloidose;    Leucemia;    Linfoma;    Neoplasias hematológicas;   

DOI  :  10.1590/S0037-86821997000500001

来源: SciELO

【 摘 要 】

Immunocompromised individuals infected with Strongyloides stercoralis may develop severe hyperinfection or disseminated disease with high mortality. Patients with hematological malignancies are at risk because of immunodepression produced either by the disease or its treatment. A prospective study was undertaken at the Hospital de Clínicas de Porto Alegre, from July 1994 to July 1995. Seventy-two (HIV negative), had 3 stool samples collected at different days and had not received recent anti-helmintic therapy. Larvae, isolated in a modified Baermann method, were found in 6 patients, with a resultant prevalence of 8.3%. No complicated strongyloidosis was documented. The positive result for S. stercoralis larvae was significantly associated (p < 0.001) with eosinophilia. Knowledge of prevalence figures and incidence of severe disease is important to adequate guidelines for empirical treatment besides the rigorous search for strongyloidosis in patients with hematological malignancies.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License