Anti-Taenia solium metacestode IgG antibodies in serum samples from inhabitants of a central-western region of Brazil

Revista do Instituto de Medicina Tropical de São Paulo

Heliana B. De Oliveira¹  Rosângela M. Rodrigues¹  Ivanildes S. C. Barcelos¹  Luciana P. Silva¹  Julia M. Costa-cruz¹ 

[1] ,Universidade Federal de Uberlândia Instituto de Ciências Biomédicas Laboratório de Parasitologia MG ,Brasil

关键词: Taenia solium;    Cysticercosis;    Immunodiagnosis;    Brazil;   

DOI  :  10.1590/S0036-46652006000100011

来源: SciELO

【 摘 要 】

A total of 354 serum samples from inhabitants who frequent the Clinical Laboratory in Catalão, Goiás, in the central-western region of Brazil, were collected from June to August, 2002. The samples were evaluated by indirect immunofluorescence antibody tests and an enzyme linked immunosorbent assay in order to detect anti-Taenia solium metacestode IgG antibodies. Reactive and inconclusive samples were tested by Western blotting (WB). Considering WB as a confirmation, the frequency of antibodies in the serum samples of the above population was 11.3% (CI 5.09 - 17.51). The immunodominant bands most frequently recognized in WB were 64-68 kDa (97.5%) and 47-52 kDa (80%). The percentage of seropositivity to cysticercosis was significantly higher for individuals residing in areas without sewage systems (p < 0.0001). In conclusion, the results indicate a probable endemic situation of cysticercosis in this population. These results reinforce the urgent need for control and prevention measures to be taken by the local public health services.

【 授权许可】

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