Concomitant rotavirus serotypes 1 and 4 infections in a diarrhoeic child from Belém, Brazil

Revista do Instituto de Medicina Tropical de São Paulo

J.d.p. Mascarenhas¹  R.h.p. Gusmão¹  Y.b. Gabbay¹  T.a.f. Monteiro¹  J.b. Gomes¹  A.c. Linhares¹ 

[1] ,Instituto Evandro Chagas Serviço de Virologia Geral Belém Pará ,Brasil

关键词: Concomitant;    rotavirus;    Serotypes 1 and 4;    Infections;   

DOI  :  10.1590/S0036-46651996000400002

来源: SciELO

【 摘 要 】

Concomitant serotypes 1 and 4 infections were detected in a 15-month old female child with community-acquired diarrhoea which lasted 7 days and coursed with moderate dehydration. The evidence for dual rotavirus infection was offered by the following findings: a) enzyme-linked immunosorbent assay (ELISA) positive reactions to both 1 and 4 serotypes; and b) extra-migrating bands at electro-phoresis of RNA in polyacrylamide gel (PAGE). These results suggest that children living under poor sanitation conditions are heavily exposed to rotavirus infections; in addition, the co-circulation of different serotypes in the same setting sustains the current concept that a rotavirus vaccine should be rnultivalent, in order to protect children against the four epidemiologically important rotavirus G serotypes.

【 授权许可】

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