The effect of chronic ingestion of ethanol on modulation of granulomatous inflammation in experimental schistosomiasis in mice

Revista do Instituto de Medicina Tropical de São Paulo

L.p.f. Castro²  E.a. Bambirra²  P.m.z. Coelho²  M.e. Silva¹ 

[1] ,UFMG Faculdade de Medicina Departamento de Anatomia Patológica e Medicina LegalBelo Horizonte MG

关键词: Schistosomiasis mansoni;    Ethanol;    Modulation of granulomatous inflammation;   

DOI  :  10.1590/S0036-46651993000500001

来源: SciELO

【 摘 要 】

We studied the role of ethanol on the modulation of liver granulomata around Schistosoma mansoni eggs in mice. Albino mice, receiving 7% ethanol as the sole drinking liquid, at 60 and 90 days post-infection, presented smaller granulomata than controls did, when sacrificed at 120 days post-infection. No differences in diameters could be observed, when ethanol was given 4 months before up to 120 days after infection. The results suggested that modulation of schistosome granulomata by ethanol ingestion varies with time and duration of drug consumption.

【 授权许可】

CC BY-NC   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License