Host cell adhesion to Schistosoma mansoni larvae in the peritoneal cavity of naive mice: histological and scanning electron microscopic studies

Revista do Instituto de Medicina Tropical de São Paulo

Alan Lane De Melo²  Conceição Ribeiro Da Silva Machado¹  Leógenes Horácio Pereira² 

[1] ,UFMG Instituto de Ciências Biológicas Departamento de Parasitologia

关键词: Schistosoma mansoni;    Cell adhesion;    Neutrophils;    Cercaria;   

DOI  :  10.1590/S0036-46651993000100003

来源: SciELO

【 摘 要 】

Cercariae of Schistosoma mansoni inoculated into the peritoneal cavity of naive mice induced host cell adhesion to their surface, but after 90 minutes the number of adherent cells sharply decreased. The cell detachment is progressive and simultaneous to the cercaria-schistosomule transformation. The histological study showed mainly neutrophils in close contact with the larvae. Mononuclear cells and some eosinophils were occasionally seen surrounding the adherent neutrophils. The scanning electron microscopy showed cells displaying twisted microvilli and several microplicae contacting or spreading over the larval surface, and larvae completely surrounded by clusters of cells. These results suggest that the neutrophils recognize molecules on the cercarial surface which induce their spreading

【 授权许可】

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