Predictive factors for anterior chamber fibrin formation after vitreoretinal surgery

Revista Brasileira de Oftalmologia

Leonardo Provetti Cunha¹  Luciana Virgínia Ferreira Costa-cunha¹  Carolina Ferreira Costa¹  Ronaldo Rocha Bastos¹  Tiago Dos Santos Prata¹  Mário Luiz Ribeiro Monteiro¹ 

关键词: Cataract/surgery;    Fibrin;    Phacoemulsification/adverse effects;    Vitrectomy/adverse effects;    Tissue plasminogen activator;    Vitreoretinal surgery;    Catarata/cirurgia;    Fibrina;    Facoemulsificação/efeitos adversos;    Vitrectomia/efeitos adversos;    Ativador de plasminogênio tecidual;    Cirurgia vitreorretiniana;   

DOI  :  10.5935/0034-7280.20140021

来源: SciELO

【 摘 要 】

Purpose: The aim of this study was to investigate possible predictive factors related to anterior chamber fibrin formation after vitreoretinal surgery in a large series of patients.Methods:The data of 185 eyes of 185 patients submitted to vitreoretinal surgery was reviewed. The following variables were evaluated: the postoperatively presence of fibrin, age, diabetes mellitus, the vitrectomy system gauge (20, 23 or 25 gauge), the type of vitreous substitute, the influence of prior surgical procedures and the combination with cataract extraction. To evaluate predictive factors for anterior chamber fibrin formation, univariate analysis was performed. A multivariate stepwise logistic regression model was adjusted to investigate factors associated with fibrin formation (p<0.05).Results:Fibrinoid anterior chamber reaction was found in 12 (6.4%) patients. For multivariate logistic regression analysis, balanced salt solution (BSS), the chance of fibrin occurrence was 5 times greater (odds ratio 4.83, CI 95% 1.302 - 17.892; p=0.019), while combination with phacoemulsification increased the chance of fibrin formation by 20 times (odds ratio 20, CI 95% 2.480 - 161.347; p=0.005). No significant difference was found regarding other variables.Conclusion: Anterior chamber fibrin formation is an unwanted complication after vitreoretinal surgery. Factors such as combined performance of phacoemulsification and the use of balanced salt solution as a vitreous substitute may predispose the occurrence of this complication.

【 授权许可】

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