Vitamin E concentration in human milk and associated factors: a literature review,

Jornal de Pediatria

Mayara S.r. Lima¹  Roberto Dimenstein¹  Karla D.s. Ribeiro¹ 

关键词: Vitamin E;    Alpha-tocopherol;    Human milk;    Lactation;    Newborn;    Vitamina E;    Alfa-tocoferol;    Leite humano;    Lactação;    Recém-nascido;   

DOI  :  10.1016/j.jped.2014.04.006

来源: SciELO

【 摘 要 】

Objective:To systematize information about vitamin E concentration in human milk and the variables associated with this composition in order to find possible causes of deficiency, supporting strategies to prevent it in postpartum women and infants.Source:Studies published between 2004 and 2014 that assayed alpha-tocopherol in human milk of healthy women by high performance liquid chromatography were evaluated. The keywords used were "vitamin E", "alpha-tocopherol", "milk, human", "lactation", and equivalents in Portuguese, in the BIREME, CAPES, PubMed, SciELO, ISI Web of Knowledge, HighWire Press, Ingenta, and Brazilian Digital Library of Theses and Dissertations databases.Summary of the findings:Of the 41 publications found on the subject, 25 whose full text was available and met the inclusion criteria were selected. The alpha-tocopherol concentrations found in milk were similar in most populations studied. The variable phase of lactation was shown to influence vitamin E content in milk, which is reduced until the mature milk appears. Maternal variables parity, anthropometric nutritional status, socioeconomic status, and habitual dietary intake did not appear to affect the alpha-tocopherol levels in milk. However, the influence of the variables maternal age, gestational age, biochemical nutritional status in alpha-tocopherol, and maternal supplementation with vitamin E had conflicting results in the literature.Conclusion:Alpha-tocopherol concentration in milk decreases during lactation, until the mature milk appears. To confirm the influence of some maternal and child variables on milk vitamin E content, further studies with adequate design are needed.

【 授权许可】

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