The genetics of the dystonias – a review based on the new classification of the dystonias

Arquivos de Neuro-Psiquiatria

Carlos Henrique F. Camargo¹  Sarah Teixeira Camargos¹  Francisco Eduardo C. Cardoso¹  Hélio Afonso G. Teive¹ 

关键词: dystonia;    genetics;    classification;    movement disorders;    distonia;    genética;    classificação;    distúrbios do movimento;   

DOI  :  10.1590/0004-282X20150030

来源: SciELO

【 摘 要 】

The definition and classification of the dystonias was recently revisited. In the new 2013 classification, the dystonias are subdivided in terms of their etiology according to whether they are the result of pathological changes or structural damage, have acquired causes or are inherited. As hereditary dystonias are clinically and genetically heterogeneous, we sought to classify them according to the new recently defined criteria. We observed that although the new classification is still the subject of much debate and controversy, it is easy to use in a logical and objective manner with the inherited dystonias. With the discovery of new genes, however, it remains to be seen whether the new classification will continue to be effective.

【 授权许可】

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