Cardiovascular variability in Mexican patients with Parkinson's disease

Arquivos de Neuro-Psiquiatria

Guillermo Delgado¹  Bruno Estañol¹  Mayela Rodríguez-violante¹  Raúl Martínez-memije¹  Óscar Infante-vázquez¹  Nancy Bertado-ramírez¹ 

关键词: Parkinson's disease;    autonomic nervous system;    heart rate variability;    blood pressure variability;    dysautonomia;    doença de Parkinson;    sistema nervoso autônomo;    variabilidade da frequência cardíaca;    variabilidade da pressão arterial;    disreflexia autonômica;   

DOI  :  10.1590/0004-282X20140125

来源: SciELO

【 摘 要 】

Cardiovascular variability (CVV) has been evaluated in patients with Parkinson's disease (PD) in other countries and exhibit ethnic differences.Objective We investigated heart rate variability (HRV) and blood pressure variability (BPV) in Mexican patients with PD. Method We further compared HRV and BPV between this group and young healthy controls (YHC) in order to estimate, for the first time in our country, the magnitude of the difference. Twenty patients were examined. Time- and frequency-domain CVV parameters were studied during supine rest (SR), active standing (AS) and controlled breathing. These measurements were compared to those of 20 YHC. Results In the three conditions tested, our study showed a decrease in almost all HRV parameters in PD patients; on the contrary, decreased BPV parameters were found less frequently and only during SR and AS. Conclusion Our results indicate that HRV is impaired in PD. Some BPV parameters are also diminished.

【 授权许可】

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