Stem cells in neurology - current perspectives

Arquivos de Neuro-Psiquiatria

Chary Ely Marquez Batista¹  Eric Domingos Mariano¹  Suely Kazue Nagahashi Marie¹  Manoel Jacobsen Teixeira¹  Matthias Morgalla¹  Marcos Tatagiba¹  Jun Li¹  Guilherme Lepski¹ 

关键词: stem cell;    neurogenesis;    neurological diseases;    stem cell therapy;    células-tronco;    neurogênese;    doenças neurológicas;    terapia com células-tronco;   

DOI  :  10.1590/0004-282X20140045

来源: SciELO

【 摘 要 】

Central nervous system (CNS) restoration is an important clinical challenge and stem cell transplantation has been considered a promising therapeutic option for many neurological diseases.Objective : The present review aims to briefly describe stem cell biology, as well as to outline the clinical application of stem cells in the treatment of diseases of the CNS. Method : Literature review of animal and human clinical experimental trials, using the following key words: “stem cell”, “neurogenesis”, “Parkinson”, “Huntington”, “amyotrophic lateral sclerosis”, “traumatic brain injury”, “spinal cord injury”, “ischemic stroke”, and “demyelinating diseases”. Conclusion : Major recent advances in stem cell research have brought us several steps closer to their effective clinical application, which aims to develop efficient ways of regenerating the damaged CNS.

【 授权许可】

CC BY   
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