Adult onset sporadic ataxias: a diagnostic challenge

Arquivos de Neuro-Psiquiatria

Orlando Graziani Povoas Barsottini¹  Marcus Vinicius Cristino De Albuquerque¹  Pedro Braga Neto¹  José Luiz Pedroso¹ 

关键词: ataxia;    sporadic ataxia;    clinical features;    diagnostic criteria;    ataxia;    ataxias esporádicas;    aspectos clínicos;    critérios diagnósticos;   

DOI  :  10.1590/0004-282X20130242

来源: SciELO

【 摘 要 】

Patients with adult onset non-familial progressive ataxia are classified in sporadic ataxia group. There are several disease categories that may manifest with sporadic ataxia: toxic causes, immune-mediated ataxias, vitamin deficiency, infectious diseases, degenerative disorders and even genetic conditions. Considering heterogeneity in the clinical spectrum of sporadic ataxias, the correct diagnosis remains a clinical challenge. In this review, the different disease categories that lead to sporadic ataxia with adult onset are discussed with special emphasis on their clinical and neuroimaging features, and diagnostic criteria.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License