Anxiety and depressive symptoms in clinically isolated syndrome and multiple sclerosis

Arquivos de Neuro-Psiquiatria

Carolina Fiorin Anhoque²  Simone Cristina Aires Domingues¹  Thiago Carvalho¹  Antônio Lúcio Teixeira¹  Renan Barros Domingues¹ 

[1] ,Microbiology Department, School of MedicineVitória ES ,Brazil

关键词: clinically isolated syndrome;    multiple sclerosis;    anxiety;    depression;    síndrome clínica isolada;    esclerose múltipla;    ansiedade;    depressão;   

DOI  :  10.1590/S0004-282X2011000700006

来源: SciELO

【 摘 要 】

Depression and anxiety have been reported in patients with multiple sclerosis (MS) and in patients with clinically isolated syndrome (CIS). However, the precise mechanisms that lead to depressive and anxiety symptoms in these patients are still unclear. In this study we evaluated with the Beck Depression Inventory (BDI) and the Beck Anxiety Inventory (BAI) patients with MS and CIS and compared them to controls. We also correlated BDI and BAI scores with clinical parameters. Kruskall-Wallis followed by Dunn's Multiple Comparison Test, Chi-square and Spearman test were used. Patients with MS had higher depressive and anxiety scores than controls. The BDI and BAI scores of patients with CIS were not significantly different from controls. There was a positive correlation between BDI, BAI and EDSS. Our results corroborate the view that MS patients have higher depression and anxiety levels than control subjects. Anxiety and depressive symptoms also seem to progress according to the severity of the disease.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License