Epileptic seizures in a descendant of Dom Pedro I

Arquivos de Neuro-Psiquiatria

Marleide Da Mota Gomes²  Heber De Souza Maia Filho¹ 

[1] ,Universidade Federal do Rio de Janeiro Faculdade de Medicina Instituto de Neurologia Deolindo CoutoRio de Janeiro RJ ,Brazil

关键词: epilepsy;    genetics;    intrauterine convulsions;    generalized epilepsy with febrile seizures;    plus;    history;    medicine;    Brazil;    epilepsia;    genética;    convulsão intra-uterina;    epilepsia generalizada com convulsões febris plus;    história;    medicina;    Brasil;   

DOI  :  10.1590/S0004-282X2010000200033

来源: SciELO

【 摘 要 】

Intrauterine seizure is a rare event. Genetic predisposition and trauma are possible risk factors. OBJECTIVE: To review and comment on the historical description of intrauterine events of a bastard daughter of Dom Pedro I (Maria Isabel Alcântara Brasileira - 1830-1896). METHOD: Review of historical facts about the health of Dom Pedro I's daughter according to primary and secondary historical data. RESULTS: According to historical accounts, Dom Pedro I's daughter suffered trauma during the intrauterine period that provoked intrauterine seizures. At the age of eight years, she developed self-limited and benign generalized epilepsy. Like her father, she had mood problems and also learning difficulties. CONCLUSION: Dona Maria Isabel's own report does not shown sufficient evidence to support the diagnosis of post-traumatic intrauterine seizures. Nevertheless, her family history suggests a genetic basis for her epilepsy.

【 授权许可】

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