Cognitive performance and mood in patients on the waiting list for liver transplantation and their relation to the model for end-stage liver disease

Arquivos de Neuro-Psiquiatria

Eliane C. Miotto²  Karina R. Campanholo¹  Melissa A.r. Machado¹  Glaucia G.r. Benute¹  Mara C.s. Lucia¹  Renério Fráguas Jr¹  Telesforo Bacchella¹  Marcel C.c. Machado¹ 

[1] ,University of São Paulo Medical School Division of Psychology and Liver Transplant Service of the Hospital das Clínicas São Paulo SP ,Brazil

关键词: hepatic encephalopathy;    cognitive deficits;    neuropsychology;    MELD;    encefalopatia hepática;    déficits cognitivos;    neuropsicologia;    MELD;   

DOI  :  10.1590/S0004-282X2010000100014

来源: SciELO

【 摘 要 】

OBJECTIVE: To investigate the links between depression and cognitive functioning in patients with Hepatitis C and other chronic liver diseases with and without the use of alcohol on the waiting list for liver transplantation and their associations with the MELD classification. METHOD: 40 patients were evaluated on a waiting list for liver transplant by a battery of neuropsychological tests, depression scales and interview at the Liver Transplant Service, of the Hospital das Clínicas University of São Paulo Medical School. RESULTS: After splitting the sample according to the education, the results showed statistical significance in the comparisons between groups of MELD > 15 and <15 in the following functions: estimated IQ, visual-spatial delayed recall and recognition as part of episodic memory and short term memory. CONCLUSION: These findings, usually found in hepatic encephalopathy, corroborated with the literature and emphasized the need to investigate in more detail the cognitive functions of these patients in order to facilitate the adoption of different conducts.

【 授权许可】

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