Arquivos de Neuro-Psiquiatria | |
Physical exercise in rats with epilepsy is protective against seizures: evidence of animal studies | |
Ricardo Mario Arida2  Fulvio Alexandre Scorza1  Vera Cristina Terra1  Roberta Monterazzo Cysneiros1  Esper Abrão Cavalheiro1  | |
[1] ,Universidade Federal de São Paulo Escola Paulista de Medicina Departamento de FisiologiaSão Paulo SP ,Brazil | |
关键词: exercise; physical training; epilepsy; seizure; rat; exercício; treinamento físico; epilepsia; crises; rato; | |
DOI : 10.1590/S0004-282X2009000600010 | |
来源: SciELO | |
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【 摘 要 】
People with epilepsy have been discouraged from participating in physical activity due to the fear that it will exacerbate seizures. Clinical and animal studies indicate a reduction of seizure frequency as well as decrease susceptibility to subsequently evoked seizures after an exercise program. Analyses from experimental studies of animals with epilepsy submitted to physical training programs were performed. In all studies the physical training was able to reduce the number of spontaneous seizures in rats with epilepsy. Seizure occurrence during exercise was relatively absent in the majority of studies. No death was found in animals with epilepsy during 1680 h of exercise. Based on these results it is plausible encouraging persons with epilepsy to non-pharmacological treatments and preventative measures such as physical exercise.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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