Cerebral abscess caused by Serratia marcescens in a premature neonate

Arquivos de Neuro-Psiquiatria

Tatiana Mattos Hirooka²  Ricardo Braganca De Vasconcellos Fontes¹  Edna Maria Diniz²  Fernando Campos Pinto¹  Hamilton Matushita¹ 

[1] ,Universidade de São Paulo Faculdade de Medicina Department of Pediatrics

关键词: brain abscess;    infant;    premature;    intensive care;    neonatal;    meningoencephalitis;    Serratia marcescens;    abcesso cerebral;    prematuro;    recém-nascido;    meningoencefalite;    Serratia marcescens;   

DOI  :  10.1590/S0004-282X2007000600021

来源: SciELO

【 摘 要 】

BACKGROUND: Cerebral abscesses are extremely rare in neonates. Serratia marcescens is an unusual cause of sepsis and neurological spread is especially ominous. PURPOSE: To report the case of a 34-week neonate who developed this rare condition and to discuss diagnostic and therapeutic measures. CASE REPRT: A 34-week male neonate sequentially developed respiratory distress syndrome, early sepsis and necrotizing enterocolitis; later cultures revealed S. marcescens. After deterioration, a cerebral abscess became evident, which revealed S. marcescens. Clinical improvement ensued after high-dose amikacin and meropenem. CONCLUSION: Clinical signs are often non-specific. Proper diagnostic measures, neurosurgical consultation and aggressive antibiotic therapy are essential for these high-risk neonates.

【 授权许可】

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