Residual signal auto-correlation to evaluate speech in Parkinson’s disease patients

Arquivos de Neuro-Psiquiatria

José Carlos Pereira²  Arthur Oscar Schelp¹  Arlindo Neto Montagnoli¹  Ana Rita Gatto¹  André Augusto Spadotto²  Lídia Raquel De Carvalho¹ 

[1] ,University of São Paulo School of Engineering of São Carlos

关键词: Parkinson’s disease;    speech analysis;    residual signal;    doença de Parkinson;    análise de fala;    sinal residual;   

DOI  :  10.1590/S0004-282X2006000600004

来源: SciELO

【 摘 要 】

OBJECTIVE: To evaluate the maximum residual signal auto-correlation also known as pitch amplitude (PA) values in patients with Parkinson’s disease (PD) patients. METHOD: The signals of 21 Parkinson’s patients were compared with 15 healthy individuals, divided according age and gender. RESULTS: Statistical difference was seen between groups for PA, 0.39 for controls and 0.25 for PD. Normal value threshold was set as 0.3; (p<0.001). In the Parkinson’s group 80.77%, and in the control group only 12.28%, had a PA<0.3 demonstrating an association between these variables. The dispersion diagram for age and PA for PD individuals showed p=0.01 and r=0.54. There was no significant difference in relation to gender and PA between groups. CONCLUSION: The significant differences in pitch’s amplitude between PD patients and healthy individuals demonstrate the methods specificity. The results showed the need of prospective controlled studies to improve the use and indications of residual signal auto-correlation to evaluate speech in PD patients.

【 授权许可】

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