Recognizing depression in patients with Parkinson’s disease: accuracy and specificity of two depression rating scale

Arquivos de Neuro-Psiquiatria

Cláudia Débora Silberman²  Jerson Laks²  Cláudia Figueiredo Capitão²  Cláudia Soares Rodrigues¹  Irene Moreira²  Eliasz Engelhardt¹ 

[1] ,Federal University of Rio de Janeiro Institute of Psychiatry Center for Alzheimer´s Disease in Related Disorders RJ ,Brazil

关键词: depression;    Parkinson’s disease;    Montgomery-Asberg rating scale;    Beck depression inventory;    depressão;    doença de Parkinson;    escala para avaliação de depressão de Montgomery-Asberg;    inventário de depressão de Beck;   

DOI  :  10.1590/S0004-282X2006000300011

来源: SciELO

【 摘 要 】

This study aimed to find cut-off scores for the Montgomery-Asberg rating scale (MADRS) and the Beck depression inventory (BDI) that can relate to specific clinical diagnoses of depression in Parkinson´s disease (PD). Mild and moderate PD patients (n=46) were evaluated for depression according to the DSM IV criteria. All patients were assessed with the MADRS and the BDI. A "receiver operating characteristics" (ROC) curve was obtained and the sensibility, specificity, positive and the negative predictive values were calculated for different cut-off scores of the MADRS and the BDI. The Kappa statistic was calculated for different cut-off scores to assess the agreement between the clinical judgment and both scales. Depression was present in 18 patients. MADRS cut-off scores of 6 and 10 showed Kappa 0.5 and 0.56, respectively. Specificity of cut-off score of 6 was 78.6% and of cut-off score of 10 was 96.4%. Kappa agreement of BDI cut-off scores of 10 and 18 were 0.36 and 0.62, respectively. Specificity was 60.7% for 10 and 92.9% for 18. Both rating scales show similar accuracy within the ROC curves (84.3% for MADRS and 79.7% for BDI). The MADRS and the BDI show a good accuracy and correlation to the clinical diagnosis when a cut-off score of 10 is used to MADRS and a cut-off score of 18 is used to BDI to recognize depression in mild to moderate PD patients. This may help clinicians to recognize depression in PD.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License