Clinical characteristics and surgical outcome of patients with temporal lobe tumors and epilepsy

Arquivos de Neuro-Psiquiatria

Carmen Lisa Jorge²  Suely K. Nagahashi-marie²  Christiane C. Pedreira²  SÉrgio Rosemberg¹  Rosa M.f. ValÉrio²  Kette D.r. Valente²  Elza M.t. Yacubian² 

[1] ,University of São Paulo Medical School Department of Neurology

关键词: epilepsy;    temporal tumor;    clinical aspects;    surgical outcome;    MRI;    epilepsia;    tumor do lobo temporal;    clínica;    prognóstico cirúrgico;    ressonância magnética;   

DOI  :  10.1590/S0004-282X2000000600004

来源: SciELO

【 摘 要 】

This is a retrospective study of 21 surgically treated patients with temporal lobe tumors and epilepsy. Evaluation included clinical data, EEG findings, structural scans, pathological diagnosis and post-surgical follow-up. There were 9 cases of ganglioglioma, 5 pilocytic astrocytoma, 3 ganglioneuroma, 2 dysembryoplastic neuroepithelial tumor, 1 pleomorphic xantoastrocytoma, and 1 meningioangiomatosis. Mean follow-up time was 22 months and outcome was evaluated according to Engel's classification; 76.2% were classified in class I and 23.8% in II and III. All patients classes II and III had been submitted to mesial and neocortical resections. There were no differences related to clinical characteristics, pathological diagnosis or duration of follow-up in patients seizure-free or not. All patients had abnormal MRI and ten of these had normal CT; the MRI characteristics were compared to pathological diagnosis and specific histological characteristics of the tumors were not discernible by MRI. We concluded that MRI was essential for the diagnosis and precise location of TL tumors. Ganglioglioma was the most frequent tumor and lesionectomy associated to mesial resection doesn't guarantee a better prognosis.

【 授权许可】

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