Surgical treatment of refractory epilepsy associated with space occupying lesions experience and review

Arquivos de Neuro-Psiquiatria

Paulo Thadeu Brainer-lima¹  Sujai Rao¹  Arthur Cukiert¹  Elza Marcia Targas Yacubian¹  Gary Gronich¹  Raul Marino Jr¹ 

[1] ,Universidade de São Paulo Hospital das Clínicas da Faculdade de Medicina Departamento de Neurologia e Neurocirurgia

关键词: brain tumor;    ganglioglioma;    refractory epilepsy;    electrocorticography;    tumor cerebral;    ganglioglioma;    epilepsia refratária;    eletrocorticografia;   

DOI  :  10.1590/S0004-282X1996000300004

来源: SciELO

【 摘 要 】

Surgery for space occupying lesions of the brain associated with intractable epilepsy represents a special problem because relief of the epilepsy is as much an operative goal as excision of the space occupying lesion itself. This study concerns 32 patients with space occupying lesions and intractable epilepsy who underwent excision of the lesion with acute intraoperative electrocorticography guided resection of the epileptogenic focus. Of the 32 patients, 16 formed a subgroup of gangliogliomas alone. The remaining were mixed lesions, predominantly benign. The duration of seizures in these patients ranged from 2 to 30 years, and the seizure frequency varied from 1 to 300 convulsions per month. The operative procedures included temporal corticectomy, amygdalo-hippocampectomy, and extratemporal corticectomies. Twenty nine patients were in Engel class I postoperatively, and three patients were in Engel class II. The findings with gangliogliomas are also considered in a separate group. This study strongly suggests that the operative procedure under electrocorticography guidance improves seizure outcome in space occuping lesions related intractable epilepsy.

【 授权许可】

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