Detection of hepatitis B virus DNA in sera from 18 alcoholic carriers of "anti-HBc alone" and response to a single dose of hepatitis B vaccine

Arquivos de Gastroenterologia

Luiz Carlos Marques De Oliveira²  Priscilla Dias Silva Abrahão¹  Sergio Borges De Amorim¹ 

[1] ,Universidade Federal de Uberlândia Faculdade de Medicina Departamento de Clínica Médica

关键词: Hepatitis B;    immunology;    Hepatitis B virus;    Alcoholism;    Hepatitis B core antigens;    Hepatite B;    imunologia;    Vírus da hepatite B.;    Alcoolismo;    Antígenos do núcleo do vírus da hepatite B;   

DOI  :  10.1590/S0004-28032008000300017

来源: SciELO

【 摘 要 】

To evaluate the possibility of occult hepatitis B virus (HBV) infection in alcoholics carriers of "anti-HBc alone", and to verify the behavior of this serological pattern after a single dose of hepatitis B vaccine, 18 alcoholics who had this serological profile were evaluated by the polymerase chain reaction method, and 17 of them were vaccined. All were negative for HBV DNA. Nine (52.9%) of those vaccined had anamnestic response, mainly those with positive anti-HBe (8/10; 80%). "Anti-HBc alone" was compatible with low levels of anti-HBs in half of the patients, and probably with false positive results for anti-HBc in the others.

【 授权许可】

CC BY-NC   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License