Arquivos Brasileiros de Oftalmologia | |
Comparison between retinal nerve fiber layer and macular thickness measured with OCT detecting progressive axonal loss following traumatic optic neuropathy | |
Leonardo Provetti Cunha2  Luciana Virginia Ferreira Costa-cunha1  Roberto Freire Santiago Malta1  Mário Luiz Ribeiro Monteiro1  | |
[1] ,Universidade de São Paulo Faculdade de Medicina Hospital das ClínicasSão Paulo SP ,Brazil | |
关键词: Optic nerve injuries; Tomography; optical coherence; Retina; Retinal ganglion cells; Nerve fibers; Macula; Visual acuity; Traumatismos do nervo óptico; Tomografia de coerência óptica; Retina; Fibras nervosas; Células ganglionares da retina; Mácula; Acuidade visual; | |
DOI : 10.1590/S0004-27492009000500004 | |
来源: SciELO | |
【 摘 要 】
PURPOSE: To compare the optical coherence tomography retinal nerve fiber layer and macular thickness measurements for detection of progressive axonal loss following acute traumatic optic neuropathy in a longitudinal study. METHODS: Three patients with unilateral traumatic optic neuropathy were evaluated sequentially after trauma. Macular and retinal nerve fiber layer thickness measurements were obtained using optical coherence tomography weekly for five weeks and around the twelfth week after trauma. RESULTS: All patients showed progressive macular and retinal nerve fiber layer thickness reduction. The mean retinal nerve fiber layer thickness on the first week was 114 μm and reduced sequentially over the first five weeks and was 46 μm on the twelfth week. For macular parameters, the mean average thickness on the first week was 248 μm and also reduced over the first five weeks and was 218 μm on the twelfth week. When compared to the initial measurement, macular thickness average reduction rate at the 12th week was 14% while peripapillary retinal nerve fiber layer thickness average reduction rate was 59%. CONCLUSIONS: Although both measurements reduce significantly after trauma, retinal nerve fiber layer thickness measurements show greater and faster retinal neural reduction if compared to macular thickness measurements in traumatic optic neuropathy.
【 授权许可】
CC BY
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