Prevalence of age-related macular degeneration in Japanese immigrants and their descendants living in Londrina (PR) - Brazil

Arquivos Brasileiros de Oftalmologia

Ana Paula Miyagusko Taba Oguido²  Antonio Marcelo Barbante Casella¹  Tiemi Matsuo¹  Eduardo Henrique De Freitas Ramos Filho¹  Rodrigo Berbel¹  Ricardo Montanheiro Alcântara Silva¹ 

[1] ,Universidade Estadual de LondrinaLondrina PR ,Brasil

关键词: Macular degeneration;    Risk factors;    Prevalence;    Macula lutea;    Ethnic groups;    Sex factors;    Middle aged;    Aged;    Aged;    80 and over;    Brazil;    Degeneração macular;    Fatores de risco;    Prevalência;    Macula lútea;    Grupos étnicos;    Fatores sexuais;    Meia-idade;    Idoso;    Idoso acima de 80 anos ou mais;    Brasil;   

DOI  :  10.1590/S0004-27492008000300013

来源: SciELO

【 摘 要 】

PURPOSE: To determine the prevalence of early and late-stage age-related macular degeneration (ARMD) and its association with risk factors such as age, gender, smoking, body mass index, hypertension and diabetes history, cataracts and pseudophakia. Design: Population-based cross-sectional study in an elderly Japanese-Brazilian population from Londrina (Paraná, Brazil). METHODS: The study included 483 (80.5%) of the 600 registered members of a local association for Japanese immigrants and their descendants, aged 60 years and up. The presence of early and late-stage age-related macular degeneration was determined using the standard protocol and the international classification system. RESULTS: The mean age of the study subjects was 71 years. The overall prevalence of age-related macular degeneration was 15.1% (CI 95%; 12-18.7). The prevalence of early-stage age-related macular degeneration was 13.8% (CI 95%; 10.9-17.3), geographic atrophy was present in 0.4% and neovascular age-related macular degeneration in 0.8%. Age-related macular degeneration was significantly (p=0.004) and linearly (p=0.001) associated with age. CONCLUSION: Our study population displays a prevalence of early and late-stage age-related macular degeneration and component lesions similar to those of other Western countries, and data suggest a higher prevalence than that reported for populations in Japan. Since the age-related macular degeneration prevalence tends to rise as the population ages, studies identifying risk factors and exploring prevention methods are becoming increasingly important.

【 授权许可】

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