Fermentation characteristics in stirred-tank reactor of exopolysaccharides with hypolipidemic activity produced by Pleurotus geesteranus5#

Anais da Academia Brasileira de Ciências

Mao Duobin¹  Ma Yuping¹  Geng Lujing¹  Zhao Aijing¹  Zheng Jianqiang¹  Xu Chunping¹ 

关键词: exopolysaccharides;    Pleurotus geesteranus;    fermentation;    hypolipidemic effect;    morphology;    exopolissacarídeos;    Pleurotus geesteranus;    fermentação;    efeito hipolipemiante;    morfologia;   

DOI  :  10.1590/0001-3765201320130037

来源: SciELO

【 摘 要 】

In this study, the hypolipidemic effect of exopolysaccharides (EPS) fromPleurotus geesteranus 5# fermenting liquor by the optimal culture conditions in a 5-L stirred-tank reactor was investigated. The hypolipidemic effect of the polysaccharide, investigated in streptozotocin induced diabetic mice, decreased plasma glucose, total cholesterol and triacylglycerol concentrations by 17.1 %, 18.8 % and 12.0 %, respectively. The results of the present investigation strongly demonstrate the potential of this polysaccharide to prevent hyperglycemia in the experimental animals. Under optimal culture conditions, the maximum concentrations of mycelial and EPS were 22.63 g/L after 7 d cultivation and 11.09 g/L after 10 d, respectively. Furthermore, the morphological parameters (i.e. mean diameter, circularity, roughness and compactness) of the pellets and the broth viscosity were characterized. It was proved that compactness of the pellet morphology (R2=0.963, p<0.01) was significantly and positively determined with mycelial biomass. Moreover, mean diameter (R2=93.3, p<0.01) and broth viscosity (R2=0.950, p<0.01) were significantly and positively determined with EPS content.

【 授权许可】

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