Flavonoids from Lonchocarpus muehlbergianus

Anais da Academia Brasileira de Ciências

Aderbal F. Magalhães²  Ana M.g.a. Tozzi¹  Eva G. Magalhães²  Ivani S. Blanco²  Maria-del-pilar C. Soriano² 

[1] ,UNICAMP Instituto de Química Departamento de Química OrgânicaCampinas SP ,Brasil

关键词: Lonchocarpus muehlbergianus;    Leguminosae;    flavonoids;    flavans;    Lonchocarpus muehlbergianus;    Leguminosae;    flavonóides;    flavanas;   

DOI  :  10.1590/S0001-37652004000400004

来源: SciELO

【 摘 要 】

The light petroleum extract from the roots of Lonchocarpus muehlbergianus Hassl contained nine flavonoids, including six new ones. These are 2,4-cis-2,4,5,8-tetramethoxy-(2´´,3´´:6,7)-furanoflavan; 2,4-cis-4-hydroxy-2,5,8-trimethoxy-(2´´,3´´:6,7)-furanoflavan; 2,4-cis-2-prenyloxy-4,5,8-trimethoxy-(2´´,3´´:6,7)-fu-ranoflavan; 2,4-cis-2-prenyloxy-4-hydroxy-5,8-dimethoxy-(2´´,3´´:6,7)-furanoflavan; 2',5',6'-trimethoxy-9-(1,1-dimethylallyoxy)-[2´´,3´´:3´,4´]-furanochalcone; 5,6-dimethoxy-(2´´,3´´:7,8)-furanoflavone, identi-fied by analysis of their spectral data (UV, IR, ¹H and 13C NMR, 2D-NMR, NOE and MS). The natural occurrence of 2,4-dioxygenated flavan derivatives is being reported for the first time. Quantitative analysis of the petrol extract, by using reversed-phase HPLC, showed that the most abundant flavonoid in the extract is 2,4-cis-2,4,5,8- tetramethoxy-(2´´,3´´:6,7)-furanoflavan.

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