International Journal of Molecular Sciences | |
Systematic Exploration of Natural and Synthetic Flavonoids for the Inhibition of |
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Suvi Manner1  Malena Skogman1  Darla Goeres2  Pia Vuorela1  | |
[1] Pharmaceutical Sciences, Department of Biosciences, Abo Akademi University, Artillerigatan 6A, 3rd Floor, Biocity, Turku FI-20520, Finland; E-Mails:;Center for Biofilm Engineering, Montana State University, Bozeman, MT 59717, USA; E-Mail: | |
关键词:
flavonoids;
flavanones;
flavans;
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DOI : 10.3390/ijms141019434 | |
来源: mdpi | |
【 摘 要 】
When single-cell (or suspended) bacteria switch into the biofilm lifestyle, they become less susceptible to antimicrobials, imposing the need for anti-biofilms research. Flavonoids are among the most extensively studied natural compounds with an unprecedented amount of bioactivity claims. Most studies focus on the antibacterial effects against suspended cells; fewer reports have researched their anti-biofilm properties. Here, a high throughput phenotypic platform was utilized to screen for the inhibitory activity of 500 flavonoids, including natural and synthetic derivatives, against
【 授权许可】
CC BY
© 2013 by the authors; licensee MDPI, Basel, Switzerland
【 预 览 】
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RO202003190033508ZK.pdf | 477KB | download |