Effect of passive exposure to cigarette smoke on blood pressure in children and adolescents: a meta-analysis of epidemiologic studies

BMC Pediatrics

Mostafa Hosseini¹  Alireza Oraii²  Mahmoud Yousefifard³  Mehdi Kazempour-Dizaji⁴  Hamidreza Jamaati⁵  Mahshid Aryanpur⁵  Hooman Sharifi⁵  Gholamreza Heydari⁵ 

[1]0000 0001 0166 0922, grid.411705.6, Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Poursina Ave, Tehran, Iran

[2]0000 0001 0166 0922, grid.411705.6, Department of Medicine, Tehran University of Medical Sciences, Tehran, Iran

[3]0000 0004 4911 7066, grid.411746.1, Physiology Research Center, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran

[4]grid.411600.2, Mycobacteriology Research Center, Biostatistics Unit, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran

[5]grid.411600.2, Tobacco Prevention and Control Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran

关键词: Hypertension;    Blood pressure;    Children and adolescent;    Smoking;   

DOI  :  10.1186/s12887-019-1506-7

来源: publisher

【 摘 要 】

BackgroundHypertension is an emerging disease in children and adolescents resulting in future morbidities. Cigarette smoking is one of the most studied contributing factors in this regard; however, there are contradictory results among different studies. Therefore, the present meta-analysis tends to assess the relationship between passive exposure to cigarette smoke and blood pressure in children and adolescents.MethodMedline, Embase, Scopus, EBSCO, and Web of Sciences were systematically reviewed for observational studies up to May, 2017, in which the relationship between cigarette smoking and hypertension were assessed in children and adolescents. The meta-analysis was performed with a fixed effect or random effects model according to the heterogeneity.ResultsTwenty-nine studies were included in present meta-analysis incorporating 192,067 children and adolescents. Active smoking (pooled OR = 0.92; 95% CI: 0.79 to 1.05) or passive exposure to cigarette smoke (pooled OR = 1.01; 95% CI: 0.93 to 1.10) were not associated with developing hypertension in the study population. Despite the fact that active cigarette smoking did not significantly affect absolute level of systolic and diastolic blood pressure, it was shown that passive exposure to cigarette smoke leads to a significant increase in absolute level of systolic blood pressure (pooled coefficient = 0.26; 95% CI: 0.12 to 0.39).ConclusionBoth active and passive cigarette smoking were not associated with developing hypertension in children and adolescents. However, passive cigarette smoke was associated with higher level of systolic blood pressure in children and adolescents.

【 授权许可】

CC BY