Microwave-Accelerated Iodination of Some Aromatic Amines, Using Urea-Hydrogen Peroxide Addition Compound (UHP) as the Oxidant†

Molecules

Maciej Sosnowski¹ 

[1] id="af1-molecules-07-00867">Chair and Laboratory of Organic Chemistry, Faculty of Pharmacy, Medical University, 1 Banacha Street, PL 02-097 Warsaw, Pola

关键词: Monoiodinated arylamines;    urea-hydrogen peroxide as oxidant;    microwave irradiation;   

DOI  :  10.3390/71200867

来源: mdpi

【 摘 要 】

A fast and simple method for the oxidative iodination of some aromatic amines, under microwave irradiation, is reported, using diiodine and the the strongly H-bonded urea-hydrogen peroxide addition compound (H₂NCONH₂···H₂O₂, UHP) as the oxidant. The reactions were carried out in boiling CHCl₃ under a reflux condenser to afford, within 10 minutes, the purified monoiodinated products in 40-80% yields.

【 授权许可】

Unknown   
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