The Synthesis of Dicationic Extended Bis-Benzimidazoles

Molecules

Zhijan Kang¹  Christine C. Dykstra² 

[1] Department of Chemistry Georgia State University, Atlanta, Georgia 30303, USA. Tel. [phone], Fax [phone].;Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, Alabama 36849, USA.

关键词: DIBAL reduction;    benzimidazoles;    amidines;    Bacillus subtilis;   

DOI  :  10.3390/90300158

来源: mdpi

【 摘 要 】

The synthesis of extended dicationic bis-benzimidazoles starting from trans‑1,2-bis(4-cyanophenyl)ethene and trans‑1,2-bis(4-cyanophenyl)cyclopropane is reported. The target diamidines show significant in vitro activity against B. subtilis.

【 授权许可】

Unknown   
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