Covalent Polymer-Drug Conjugates

Molecules

CarlosElvira¹  AlbertoGallardo¹  Julio San Roman¹ 

[1] Institute of Polymer Science and Technology (CSIC), Juan de la Cierva 3, 28006 Madrid, Spain

关键词: drug delivery system;    DDS;    polymer-drug;    polymer-protein;    conjugates;   

DOI  :  10.3390/10010114

来源: mdpi

【 摘 要 】

In this work, polymer-drugs conjugates used as drug delivery systems (DDS) are revised attending to their chemical conjugation. Namely, the classification of this type of DDS is based on the conjugation sites of the reactive groups (i.e., via end groups or pendant polymer groups).  Advantages and limitations of these types of DDS are discussed through representative examples of polymer-drugs and polymer-proteins conjugates recently developed.

【 授权许可】

Unknown   
© 2005 by MDPI (http://www.mdpi.org).