An Aromatic Iodination Method with Iodic Acid Used as the Only Iodinating Reagent†

Molecules

Barbara Krassowska-Swiebocka¹  Grazyna Prokopienko¹ 

[1] Chair and Laboratory of Organic Chemistry, Faculty of Pharmacy, Medical University, Banacha 1, PL 02-097 Warsaw, Poland

关键词: Arenes;    iodoarenes;    aromatic iodination;    iodic acid as reactant;    iodinating agent;   

DOI  :  10.3390/10020394

来源: mdpi

【 摘 要 】

Benzene, halobenzenes, and a number of more or less deactivated arenes, including nitrobenzene, readily reacted in anhydrous HIO₃/AcOH/Ac₂O/conc. H₂SO₄ mixtures to probably give ArIO₂ intermediates or other hypervalent species (not isolated). The final reaction mixtures were poured into excess aq. Na₂SO₃ solution (a reductant) to give the purified iodinated products in 39-83% yields.

【 授权许可】

Unknown   
© 2005 by MDPI (http://www.mdpi.org).