Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species†

Molecules

I. A. Rivero¹  K. Espinoza² 

[1] id="af1-molecules-09-00609">Centro de Graduados e Investigación, Instituto Tecnológico de Tijuana, Apartado Postal 1166. 22000. Tijuana, B.C. Méxic

关键词: Quinazoline-2;    4-dione;    alkaloids;    triphosgene;    anti-hypertensive activity;   

DOI  :  10.3390/90700609

来源: mdpi

【 摘 要 】

Quinazolinone and quinazolinedione derivatives are of considerable interest due to their wide array of pharmacological properties. In this paper we report the synthesis of ten quinazolinediones. The previous isolation of two of these compounds, namely 1-methyl-3-(2'-phenylethyl)-1H,3H-quinazoline-2,4-dione and 1-methyl-3-[2'-(4'-methoxyphenyl)ethyl]-lH,3H-quinazoline-2,4-dione, from the seed husks of Mexican Zanthoxylum species has been reported

【 授权许可】

Unknown   
© 2004 by MDPI (http:www.mdpi.org).