Microwave Assisted Synthesis of N-Arylheterocyclic Substituted-4-aminoquinazoline Derivatives

Molecules

Gang Liu²  Song Yang²  Baoan Song¹  Wei Xue²  Deyu Hu²  Linhong Jin² 

[1] Center for Research and Development of Fine Chemicals, Guizhou University, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guiyang, 550025, P. R. China E-mails

关键词: 4-Aminoquinazoline;    Heterocyclic moiety;    Microwave irradiation;   

DOI  :  10.3390/11040272

来源: mdpi

【 摘 要 】

A simple, efficient, and general method has been developed for the synthesis of various N-aryl heterocylic substituted-4-aminoquinazoline compounds from 4-chloro- quinazoline and aryl heterocyclic amines under microwave irradiation using 2-propanol as solvent. The advantages of the use of microwave irradiation in relation to the classical method were demonstrated.

【 授权许可】

Unknown   
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