Microwave Assisted N-Alkenyl Condensation between Pyrrolidine-2-thione and Various Aldehydes

Bulletin of the Korean chemical society

Ho-Joon Lee¹  Mi-ja Park¹  Tae-Woo Kwon¹  Chung-Gi Kim¹  Ki-Won Kim¹ 

关键词: Microwave irradiation;    Pyrrolidine-2-thione;    N-Alkenyl pyrrolidine-2-thiones;    N-Alkenyl condensation;   

DOI  :  

学科分类：化学（综合）

来源: Korean Chemical Society

【 摘 要 】

A series of N-alkenyl pyrrolidine-2-thiones were synthesized by the reaction between pyrrolidine-2-thione and various aldehydes such as n-propanal, isopropanal, n-butanal, n-hexanal, n-octanal and phenylacetaldehyde in 32-86% yields using microwave irradiation technique. Only one structural E isomers were predominantly formed within 15 minutes in chlorobenezene/p-toluenesulfonic acid monohydrate.

【 授权许可】

Unknown