Leufolins A and B, Potent Butyrylcholinesterase-inhibiting Flavonoid Glucosides from Leucas urticifolia

Molecules

Atia-tun Noor¹  Itrat Fatima¹  Ijaz Ahmad²  Abdul Malik¹  Nighat Afza³  Lubna Iqbal³  Mehreen Latif³ 

[1] International Centre for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan;Medicinal Botanic Centre, PCSIR Labs. Complex Peshawar, Peshawar, N.W.F.P, Pakistan;Pharmaceutical Research Centre, PCSIR Labs. Complex, Karachi-75280, Pakistan

关键词: Leucas urticifolia;    Lamiaceae;    Leufolin A;    Leufolin B;    Butyrylcholinesterase;    Inhibitory activity;   

DOI  :  10.3390/12071447

来源: mdpi

【 摘 要 】

New flavonoidal glucosides leufolins A (1) and B (2), have been isolated from the ethyl acetate soluble fraction of the whole plants of Leucas urticifolia. Their structures were elucidated on the basis of extensive analysis of nuclear magnetic resonance (1D and 2D NMR) spectral data. Both of these compounds exhiited significant inhibitory potential against the enzyme butyrylcholinesterase.

【 授权许可】

Unknown   
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