Chemical Composition and Antioxidant Activity of Tánara Ótó (Dracocephalum palmatum Stephan), a Medicinal Plant Used by the North-Yakutian Nomads

Molecules

Daniil N. Olennikov³  Nadezhda K. Chirikova²  Zhanna M. Okhlopkova¹ 

[1] Department of Biology, North-Eastern Federal University, 58 Belinsky Str., Yakutsk 677-027, Russia; E-Mails:;Department of Biochemistry and Biotechnology, North-Eastern Federal University, 58 Belinsky Str., Yakutsk 677-027, Russia; E-Mail:;Institute of General and Experimental Biology, Siberian Division, Russian Academy of Science, Sakh’yanovoy str., 6, Ulan-Ude 670047, Russia

关键词: Dracocephalum palmatum Stephan;    Lamiaceae;    North-Yakutian nomads;    flavonoids;    phenylpropanoids;    antioxidant activity;   

DOI  :  10.3390/molecules181114105

来源: mdpi

【 摘 要 】

Dracocephalum palmatum Stephan (Lamiaceae) is a medicinal plant used by the North-Yakutian nomads. From the crude ethanolic extract of the aerial parts of this plant, 23 compounds (phenylpropanoids, coumarins, flavonoids, and triterpenes) were isolated. Among these, eight compounds (salvianolic acid B, caftaric acid, cichoric acid, umbelliferone, aesculetin, apigenin-7-O-β-d-glucuronopyranoside, isorhoifolin, and luteolin-4'-O-β-d-glucopyranoside) were detected for the first time in the genus Dracocephalum. Their structures were elucidated based on chemical and spectral data. The levels of most of the compounds detected in the cultivated sample were close to that of the wild sample, indicating the reproducibility of the biologically active compounds of D. palmatum through cultivation. Investigation into the biological activity of D. palmatum under in vitro conditions demonstrated that its extracts have a strong antioxidant effect due to the presence of high concentrations of phenolic compounds.

【 授权许可】

CC BY   
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