Ring Contracting Sulfur Extrusion from Oxidized Phenothiazine Ring Systems

Molecules

Steven C. Farmer¹ 

关键词: Phenothiazine;    Desulfurization;    Sulfoxides;    Sulfones;   

DOI  :  10.3390/molecules13061345

来源: mdpi

【 摘 要 】

Lithium, used in conjunction with sodium metal, produces a high yield of carbazole when reacted with phenothiazine-5-oxide or phenothiazine-5,5-dioxide. A high yield of 9-ethylcarbazole is also produced when these reagents react with 10-ethyl-phenothiazine, 10-ethylphenothiazine-5-oxide, and 10-ethylphenothiazine-5,5-dioxide. Degassed Raney nickel produces carbazole in high yield when reacted with phenothiazine and phenothiazine-5-oxide. A moderate yield of 9-ethylcarbazole is produced when n‑butyllithium is reacted with 10-ethylphenothiazine-5-oxide.

【 授权许可】

CC BY   
© 2008 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.