Bulletin of the Korean chemical society | |
Synthesis, Anthelmintic and Anti-inflammatory Activities of Some Novel Imidazothiazole Sulfides and Sulfones | |
Nitinkumar S Shetty1  Imtiyaz Ahmed M Khazi1  Chuljin Ahn1  | |
关键词: Imidazo[2; 1-b]thiazole; Sulfides; Sulfones; Anthelmintic activity; Anti-inflammatory activity; | |
DOI : | |
学科分类:化学(综合) | |
来源: Korean Chemical Society | |
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【 摘 要 】
A series of new 6-aryl-3-(3,4-dimethoxy-phenyl)-2-phenylsulfanyl-imidazo[2,1-b]-thiazole (5a-c) and 6-aryl-2- benzenesulfonyl-3-(3,4-dimethoxy-phenyl)imidazo[2,1-b]- thiazole (6a-c) have been prepared and characterized by analytical and spectral methods. The title compounds 5a-c and 6a-c were obtained by the reaction of 4-(3,4- dimethoxy-phenyl)-5-phenylsulfanyl-thiazol-2-ylamine (3) and 5-benzenesulfonyl-4-(3,4-dimethoxy -phenyl)thiazol- 2-ylamine (4) with various phenacyl bromides in anhydrous ethanol. These newly synthesized compounds (5a-c and 6a-c) were screened for their anthelmintic and anti-inflammatory activities, where they have displayed better activities.
【 授权许可】
Unknown
【 预 览 】
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RO201912010242438ZK.pdf | 331KB | ![]() |