Species-specific Fungal DNA in Airborne Dust as Surrogate for Occupational Mycotoxin Exposure?

International Journal of Molecular Sciences

关键词: Occupational exposure;    mycotoxin exposure;    inhalation;    PCR;    fungi;   

DOI  :  10.3390/ijms9122543

来源: mdpi

【 摘 要 】

Possible health risks associated with occupational inhalation of mycotoxin-containing dust remain largely unknown, partly because methods for mycotoxin detection are not sensitive enough for the small dust masses obtained by personal sampling, which is needed for inhalable exposure measurements. Specific and sensitive PCR detection of fungi with mycotoxin-producing potential seem to be a good surrogate for occupational exposure measurements that include all fungal structures independent of morphology and cultivability. Results should, however, be interpreted with caution due to variable correlations with mycotoxin concentrations.

【 授权许可】

CC BY   
© 2008 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).