Biodegradable Polydepsipeptides

International Journal of Molecular Sciences

Yakai Feng¹ 

关键词: Polydepsipeptides;    morpholine-2;    5-dione;    biomaterials;    biodegradation;    ring-opening polymerization;   

DOI  :  10.3390/ijms10020589

来源: mdpi

【 摘 要 】

This paper reviews the synthesis, characterization, biodegradation and usage of bioresorbable polymers based on polydepsipeptides. The ring-opening polymerization of morpholine-2,5-dione derivatives using organic Sn and enzyme lipase is discussed. The dependence of the macroscopic properties of the block copolymers on their structure is also presented. Bioresorbable polymers based on polydepsipeptides could be used as biomaterials in drug controlled release, tissue engineering scaffolding and shape-memory materials.

【 授权许可】

CC BY   
© 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.