Effect of Ionic Liquids as the Mobile Phase Additives on the HPLC Resolution of Four Active Compounds from Sophora flavescens Ait

Molecules

Minglei Tian¹  Junyu Liu¹ 

[1] id="af1-molecules-14-02127">Department of Chemical Engineering, Inha University, Incheon, 402–751, Kor

关键词: ionic liquid;    retention;    resolution;    HPLC;    Sophora flavescens Ait;   

DOI  :  10.3390/molecules14062127

来源: mdpi

【 摘 要 】

The retention behaviour of four active compounds from Sophora Flavescens Ait using three ionic liquids as mobile phase modifiers was examined. The effect of the pH and the amount of ionic liquid modifier on the retention of these compounds was determined in methanol/water (v/v) as the mobile phase containing different ionic liquids ranging in concentration from 0.1 mmol/L to 3.0 mmol/L. The ionic liquids showed promise as additives in high-performance liquid chromatography.

【 授权许可】

CC BY   
© 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.