An In Situ Formation of Ionic Liquid for Enrichment of Triazole Fungicides in Food Applications Followed by HPLC Determination

Molecules

卷:27

Jitlada Vichapong¹  Rawikan Kachangoon¹  Yanawath Santaladchaiyakit²  Supalax Srijaranai³ 

[1] Creative Chemistry and Innovation Research Unit, Department of Chemistry and Center of Excellent for Innovation in Chemistry, Faculty of Science, Mahasarakham University, Maha Sarakham 44150, Thailand;

[2] Department of Chemistry, Faculty of Engineering, Rajamangala University of Technology Isan, Khon Kaen Campus, Khon Kaen 40000, Thailand;

[3] Materials Chemistry Research Center, Department of Chemistry and Center of Excellent for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand;

关键词: ionic liquid;    in situ extraction;    triazole fungicides;    extraction;    HPLC;   

DOI  :  10.3390/molecules27113416

来源: DOAJ

【 摘 要 】

An in situ formation of ionic liquid was used for preconcentration of four triazole fungicides in food samples. The microextraction method was used for the first time in the literature for preconcentration of triazole fungicides. In the developed method, tributylhexadecylphosphonium bromide ([P₄₄₄₁₂]Br) and potassium hexafluorophosphate (KPF₆) were used for the formation of hydrophobic ionic liquid. After centrifugation, the fine microdroplets were produced in one step, providing the extraction step in a quick and environmentally friendly manner. The functional group of the hydrophobic ionic liquid was investigated using FT-IR. Various extraction parameters were studied and optimized. In the extraction method, 0.01 g of [P₄₄₄₁₂]Br and 0.01 g of KPF₆, centrifugation at 4500 rpm for 10 min were used. The optimized technique provided a good linear range (90–1000 μg L⁻¹) and high extraction recovery, with a low limit of detection (30–50 μg L⁻¹). Methods for the proposed in situ formation of ionic liquid were successfully applied to honey, fruit juice, and egg matrices. The recoveries were obtained in a satisfactory range of 62–112%. The results confirmed the suitability of the proposed microextraction method for selective extraction and quantification of triazole fungicides.

【 授权许可】

Unknown