Dairy-Rich Diets Augment Fat Loss on an Energy-Restricted Diet: A Multicenter Trial

Nutrients

Michael B. Zemel⁵  Dorothy Teegarden¹  Marta Van Loan³  Dale A. Schoeller²  Velimir Matkovic⁴  Roseann M. Lyle¹ 

[1] Purdue University, 700 W. State St., W. Lafayette, IN 47907, USA;The University of Wisconsin, 1415 Linden Drive, Madison, WI 53706, USA;USDA, ARS, Western Human Nutrition Research Center, 430 W. Health Sciences Drive, Davis, CA 95616, USA;Ohio State University, 480 W. 9^th Ave, Columbus, OH 43210, USA;;The University of Tennessee, Knoxville, TN 37996, USA

关键词: calcium;    dairy;    energy restriction;    multi-center;    vitamin D;   

DOI  :  10.3390/nu1010083

来源: mdpi

【 摘 要 】

A 12-week randomized controlled multi-center clinical trial was conducted in 106 overweight and obese adults. Diets were designed to produce a 2,093 kJ/day energy deficit with either low calcium (LC; ~600 mg/day), high calcium (HC; ~1,400 mg/day), or high dairy (HD; three dairy servings, diet totaling ~1,400 mg/day). Ninety-three subjects completed the trial, and 68 met all a priori weekly compliance criteria. Both HC and HD contained comparable levels of calcium, but HC was only ~30% as effective as HD in suppressing 1,25-(OH)₂D and exerted no significant effects on weight loss or body composition compared to LC. In the group that met compliance criteria, HD resulted in ~two-fold augmentation of fat loss compared to LC and HC (HD: -4.43 ± 0.53 kg; LC: -2.69 ± 0.0.53 kg; HC: -2.23 ± 0.73kg, p < 0.025); assessment of all completers and an intent-to-treat analysis produced similar trends. HD augmentated central (trunk) fat loss (HD: -2.38 ± 0.30 kg; HC: -1.42 ± 0.30 kg; LC: -1.36 ± 0.42 kg, p < 0.05) and waist circumference (HD: -7.65 ± 0.75 cm; LC: -4.92 ± 0.74 cm; LC: -4.95 ± 1.05 cm, p < 0.025). Similar effects were noted among all subjects completing the study and in an intent-to-treat analysis. These data indicate that dairy-rich diets augment weight loss by targeting the fat compartment during energy restriction.

【 授权许可】

CC BY   
© 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.