Monitoring Healthy Metabolic Trajectories with Nutritional Metabonomics

Nutrients

Sebastiano Collino¹  François-Pierre J. Martin¹  Sunil Kochhar¹ 

[1] BioAnalytical Science, Metabonomics & Biomarkers, Nestlé Research Center, PO Box 44, CH-1000 Lausanne 26, Switzerland;

关键词: GC (Gas Chromatography);    gut microbiota;    MS (Mass Spectrometry);    metabolomics;    metabonomics;    metabotypes;    NMR (Nuclear Magnetic Resonance) Spectroscopy;    nutrimetabonomics;    personalized nutrition;    UPLC (Ultra Performance Liquid Chromatography);   

DOI  :  10.3390/nu1010101

来源: mdpi

【 摘 要 】

Metabonomics is a well established analytical approach for the analysis of physiological regulatory processes via the metabolic profiling of biofluids and tissues in living organisms. Its potential is fully exploited in the field of “nutrimetabonomics” that aims at assessing the metabolic effects of active ingredients and foods in individuals. Yet, one of the greatest challenges in nutrition research is to decipher the critical interactions between mammalian organisms and environmental factors, including the gut microbiota. “Nutrimetabonomics” is today foreseen as a powerful approach for future nutritional programs tailored at health maintenance and disease prevention.

【 授权许可】

CC BY   
© 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.