Synthesis and Antifungal Activity of 5-Chloro-6-Phenylpyridazin-3(2H)-one Derivatives

Molecules

Jian Wu¹  Baoan Song¹  Hongjun Chen¹  Pinaki Bhadury¹ 

[1] Key Laboratory of Green Pesticide and Agriculture Bioengineering, Ministry of Education, Research and Development Center for Fine Chemicals, Guizhou University, Guiyang 550025, China

关键词: pyridazine derivatives;    synthesis;    antifungal activity;   

DOI  :  10.3390/molecules14093676

来源: mdpi

【 摘 要 】

An effective method has been developed for the preparation under mild conditions of novel pyridazine derivatives from the easily accessible starting materials mucochloric acid and benzene. All the synthesized compounds were fully characterized and some of them displayed good antifungal activities against G. zeae, F. oxysporum and C. mandshurica in preliminary antifungal activity tests.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.