Silica Sulfuric Acid Promotes Aza-Michael Addition Reactions under Solvent-Free Condition as a Heterogeneous and Reusable Catalyst

Molecules

Yan Wang¹  Yan-Qin Yuan¹ 

[1] Department of Chemistry and Biology, Lishui University, Lishui, Zhejiang 323000, China

关键词: amines;    thiols;    silica sulfuric acid (SSA);    Michael reaction;    α;    β-unsaturated olefins;   

DOI  :  10.3390/molecules14114779

来源: mdpi

【 摘 要 】

A highly efficient, inexpensive, recyclable, convenient, and green protocol for chemoselective aza-Michael addition reactions of amines/thiols to α,β-unsaturated compounds using silica sulfuric acid (SSA or SiO₂-SO₃H) was developed. This method is simple, convenient and the title compounds are produced in good to excellent yields.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.