Functional Genomics of Allergen Gene Families in Fruits

Nutrients

Fatemeh Maghuly¹  Gorji Marzban¹ 

[1] Plant Biotechnology Unit, IAM, Department of Biotechnology, VIBT BOKU, 1190 Vienna, Austria;

关键词: temperate fruits;    small fruits;    pathogenesis-related proteins;    Southern Blot;    RT-PCR;    ELISA;    Immuno Tissue Printing;    Western Blot;    2D-electrophoresis;    Agrobacterium mediated transformation;    RNAi approach;   

DOI  :  10.3390/nu1020119

来源: mdpi

【 摘 要 】

Fruit consumption is encouraged for health reasons; however, fruits may harbour a series of allergenic proteins that may cause discomfort or even represent serious threats to certain individuals. Thus, the identification and characterization of allergens in fruits requires novel approaches involving genomic and proteomic tools. Since avoidance of fruits also negatively affects the quality of patients’ lives, biotechnological interventions are ongoing to produce low allergenic fruits by down regulating specific genes. In this respect, the control of proteins associated with allergenicity could be achieved by fine tuning the spatial and temporal expression of the relevant genes.

【 授权许可】

CC BY   
© 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.